Crystal-packing analysis of hexagonal apoA-IV64–335 crystals. (a) The asymmetric unit contains a dimer, chains A and B, that domain swaps through a long helix that extends the length of the molecule. Two dimer molecules stack vertically by a slight offset, forming a helical wall. This wall then intersects adjacent walls at 116°, creating a honeycomb-like lattice. (b) Top view of the honeycomb-like lattice looking down the long unit-cell dimension. Large solvent channels are the result of helices intersecting. (c) Side view of (b) looking perpendicular to the long axis.