The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery

Moynie, L.; Schnell, R.; McMahon, S.A.; Sandalova, T.; Boulkerou, W.A.; Schmidberger, J.W.; Alphey, M.; Cukier, C.; Duthie, F.; Kopec, J.; Liu, H.; Jacewicz, A.; Hunter, W.N.; Naismith, J.H.; Schneider, G.

doi:10.1107/S1744309112044739

Figure 3
Schematic view of the structure of the putative aldo-keto reductase PA4992. Bound NADP⁺ and the putative catalytic triad are shown as stick models. The nicotinamide ribose moiety of NADP⁺ is not shown as it is disordered in the crystals.