Figure 1
Architecture of the Keap1 Kelch domain. The six individual blades of the highly symmetric [beta]-propeller (grey ribbons) are connected by the interblade A-D loops (red); the B-C loops are coloured orange. The Nrf2-binding site is formed by the interblade A-D loops and the B-C loops. The small [beta]-sheet inserted into the B-C loop of the second blade is coloured blue. All figures were created with PyMOL (Schrödinger).  [article HTML]

© International Union of Crystallography 2013