The following articles are a selection of those recently accepted for publication in Acta Crystallographica Section F: Structural Biology Communications.
Crystal structure of an IclR homologue from Microbacterium sp. strain HM58-2
The crystal structure of an IclR homologue from Microbacterium sp. strain HM58-2 was determined at 2.1 Å resolution. It revealed a unique tetramer conformation, which may represent one of the multiple conformations in transcriptional regulation.
Crystal structure of truncated human coatomer protein complex subunit ζ1 (Copζ1)
Selective targeting of the ζ1 subunit of the human coatomer protein complex I (Copζ1) is a promising avenue for anticancer therapy, as knockouts of ζ1 have been shown to specifically kill both proliferating and nondividing tumour-cell populations. In order to provide a structural basis for rational drug design, the high-resolution crystal structure of Copζ1 is reported.