J. Appl. Cryst. (2013). 46, 795-797 [ doi:10.1107/S0021889813008030 ]
Abstract: Protein crystallization conditions that resulted in crystal structures published by scientists at the MRC Laboratory of Molecular Biology (MRC-LMB, Cambridge, UK) have been analysed. It was observed that the more often a crystallization reagent had been used to formulate the initial conditions, the more often it was found in the reported conditions that yielded diffraction quality crystals. The present analysis shows that, despite the broad variety of reagents, they have the same impact overall on the yield of crystal structures. More interestingly, the correlation implies that, although the initial crystallization screen may be considered very large, it is an under-sampled combinatorial approach.
Keywords: Macromolecular crystallization; screen formulation; crystallization reagents; crystal structure.
Microsoft Excel (XLS) file (327.0 kbytes)
Open Spreadsheet Text (ODS) file (56.4 kbytes)
Microsoft Excel (XLS) file (52.0 kbytes)
Open Spreadsheet Text (ODS) file (21.5 kbytes)
Microsoft Excel (XLS) file (28.0 kbytes)
Open Spreadsheet Text (ODS) file (17.6 kbytes)
To open or display or play some files, you may need to set your browser up to use the appropriate software. See the full list of file types for an explanation of the different file types and their related mime types and, where available links to sites from where the appropriate software may be obtained.
The download button will force most browsers to prompt for a file name to store the data on your hard disk.
Where possible, images are represented by thumbnails.
Copyright © International Union of Crystallography