Figure 3
(a) Effects of the therapy on tumor growth for animals bearing a large tumor (mean volume 480 ± 33 mm3) at the moment of the treatment. Effects of the intratumoral injection of 2.5 µg of cisplatin alone (group 2; black down-triangles), the radiotherapy alone (group 3; blue up-triangles), the whole treatment with 2.5 µg of cisplatin (group 4; green diamonds) and no treatment (group 1; red squares) on the tumor growth. (b) Effects of the therapy on tumor growth for animals bearing a small tumor (mean volume 106 ± 11 mm3) at the moment of the treatment. Effects of the intratumoral injection of 2.5 µg of cisplatin alone (group 6; black down-triangles), the radiotherapy alone (group 7; blue up-triangles), the whole treatment with 2.5 µg of cisplatin (group 8; green diamonds) and no treatment (group 5; red squares) on the tumor growth. For each group the tumor volume was normalized to 100 at the moment of the treatment. &: p < 0.05 whole treatment versus control; #: p < 0.05 irradiation alone versus control; +: p < 0.05 whole treatment versus cisplatin alone; £: p < 0.05 irradiation alone versus cisplatin alone; $: p < 0.05 whole treatment versus irradiation alone; [mu]: p < 0.05 cisplatin alone versus control; unpaired two-tailed Student's t-test.  [article HTML]