Cryo-EM/ET observations of the RDV structures within the insect vector cell. (a) Low-magnification cryo-EM image of the RDV-infected NC24 cell cultured on the EM grid. Bar: 2 µm. (b) High-magnification cryo-EM image of the boxed region in (a). Bar: 400 nm. (c) A slice through the reconstructed tomographic volume obtained from the area highlighted in (b). Black arrows indicate the RDV particles within the multivesicular body (MVB).