The formation of paracetamol (acetaminophen) adducts with hydrogen-bond acceptors

Oswald, I.D.H.; Allan, D.R.; McGregor, P.A.; Motherwell, W.D.S.; Parsons, S.; Pulham, C.R.

doi:10.1107/S0108768102015987

Acta Crystallographica Section B
Acta Crystallographica
Section B STRUCTURAL SCIENCE, CRYSTAL ENGINEERING AND MATERIALS

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Figure 5
Paracetamol:morpholine adduct viewed along the a axis. The c direction runs from left to right, the b direction up and down. The labels A and B refer to the crystallographically independent paracetamol molecules referred to in the text. The C(4) chains referred to in the text run from left to right and are linked together by hydrogen bonds between opposed OH groups. This forms a grid-like array with the morpholine molecules residing in the grid cavities. The dihedral angles between the amide and phenyl mean planes in the two independent paracetamol molecules are 36.03 (6)° and 3.04 (3)° for molecules A and B, respectively.

STRUCTURAL SCIENCE
CRYSTAL ENGINEERING
MATERIALS

ISSN: 2052-5206

Volume 58| Part 6| November 2002| Pages 1057-1066

doi:10.1107/S0108768102015987

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