Figure 1
Labelling of atoms and torsion angle in piracetam. θ1 (torsion angles defined by C2—N1—C6—C7) and θ2 (N1—C6—C7—N8) are considered to be the major variable torsion angles, and θ3 (C6—C7—N8—H angle closest to 0°) and the torsion angles in the pyrrolidine ring are considered to be the minor variable torsion angles. |