From a binary salt to salt co-crystals of antibacterial agent lomefloxacin with improved solubility and bioavailability

Zhang, Z.-H.; Zhang, Q.; Zhang, Q.-Q.; Chen, C.; He, M.-Y.; Chen, Q.; Song, G.-Q.; Xuan, X.-P.; Huang, X.-F.

doi:10.1107/S2052520615011191

Acta Crystallographica Section B
Acta Crystallographica
Section B STRUCTURAL SCIENCE, CRYSTAL ENGINEERING AND MATERIALS

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Figure 4
(a) Molecular structure of (1). (b) A perspective view of the hydrogen-bonding interactions between piperazine groups of lomefloxacin and the carboxylate–water tape. (c) A two-dimensional supramolecular network constructed by multiple N—H⋯O and O—H⋯O hydrogen bonds (highlighted as purple dashed lines).

STRUCTURAL SCIENCE
CRYSTAL ENGINEERING
MATERIALS

ISSN: 2052-5206

Volume 71| Part 4| July 2015| Pages 437-446

doi:10.1107/S2052520615011191

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