Figure 1
Covalent structure of the WC base pairs discussed in this work, with standard atom numbering. Hydrogen atoms are marked to define the covalent/tautomeric topology but they are not numbered as they are not included in the generated libraries of stereochemical restraints. The AU base pair (not shown) has the same atom numbering as the AT pair, except that it does not have the CM methyl substituent at the pyrimidine (U) base. Hydrogen bonds are marked by dashed lines. |