Figure 9
A schematic structural model of RDV obtained by the present structure analysis. The outer radius of about 350 Å, 27 Å thickness of the inner core shell and RNA shell with 230 Å radius and 20 Å thickness were determined from the electron-density map at 20 Å resolution. The capsid outer shell of the intact RDV is composed of P8 trimers at quasi-threefold axes and P2 at threefold axes on the spherical surface of T = 13 icosahedron. Broken circles are P2 in the intact RDV. They have been removed from RDV used for the present study. P7 molecules cluster around each fivefold axis inside the core shell. |