Figure 4
Stereo diagrams of the hydrophobic binding pockets of FKBP12.6 and FKBP12. All residues and surfaces within 4 Å of rapamycin are shown. Ribbons and carbon are white in FKBP12.6 and gray in FKBP12. O atoms and N atoms are red and blue, respectively, in both. Hydrogen bonds are shown as dashed black lines. |