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Figure 3
Stereo representation of the superposition of the hRARγLBD/CD564 complex and the ternary complex PPARγ LBD/SRC-1 peptide/BRL49653 as obtained by a least-squares fit of the crystal structures illustrates that the dodecyl-α-D-maltoside molecule binds at the coactivator-binding site of RAR; the PPAR protein part is coloured red. H10 of hRARγsym (blue) exhibits the same orientation as the SRC-1 helix (yellow). |