 | Acta Crystallographica Section D Acta Crystallographica Section D BIOLOGICAL CRYSTALLOGRAPHY |
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![[Figure 8]](ba0040fig8mag.jpg)
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Figure 8
(a) Stereoview of the cryo-EM reconstruction showing the complex of PV1 with human CD155. The outline of one geometric icosahedral asymmetric unit is shown. Note that the receptor leans toward the southeast. (b) Stereoview of the cryo-EM reconstruction showing the complex of HRV16 with its ICAM-1 receptor. The outline of one geometric icosahedral asymmetric unit is shown. Note that the receptor leans towards the southwest. (c) Stereoview of a cryo-EM reconstruction of PV1, also showing the geometric icosahedral asymmetric unit. Note the asymmetric shape of the canyon with its most southerly point slightly east of center (arrow) and the smaller peak southwest of the canyon (arrow). These features establish the correct hand of the reconstructions in (a) and (b) and are consistent with the X-ray results, where the absolute hand is known. (d) Density (green) representing one CD155 molecule (black) fitted with the Cα backbone structure of the closest homologous structure found in the PDB for each of the three domains. Shown also is the difference map (blue) between the cryo-EM density and the unglycosylated CD155 model to show the sites of glycosylation. The potential glycosylation sites are shown on the CD155 backbone (red). [Reprinted by permission from He et al. (2000  ), Proc. Natl Acad. Sci. USA, 97, 79–84. Copyright (2000) National Academy of Sciences, USA.] |
![[Figure 8]](ba0040fig8.jpg)
| BIOLOGICAL CRYSTALLOGRAPHY |
ISSN: 1399-0047
