Figure 3
Schematic diagrams of the epitopes of the neutralizing MAb-E3 on the RHDV capsid. The icosahedral axes are marked 2, 3 and 5 and the local two- and threefold axes are marked with symbols. In (a), three dimeric arches of the capsid are represented in dark grey and possible pairs of binding sites for one MAb are shown linked by lines in different shades of grey. The overlapping epitopes on each arch are indicated. A schematic diagram of one of the many possible distributions of mAb-E3 on the capsid is shown in (b). (Adapted from Fig. 6 in Thouvenin et al., 1997.) |