Figure 1
Bacteriophage SPP1 assembly pathway. A spherical procapsid is assembled by copolymerization of gp11 (scaffolding protein) and gp13 (major head protein) initiated at a specialized vertex characterized by the presence of gp6 (portal protein) and gp7 (accessory protein) (Lurz et al., 1997; Dröge et al., 2000). The symmetry and EM structures of the gp6 cyclical oligomer are shown for two morphogenetic steps of viral assembly (Orlova et al., 1999; Orlova et al., unpublished results). |