Figure 4
Effect of solvent content on map-likelihood phasing with a partially incorrect mask. Mean true figure of merit (〈cosΔφ〉) is plotted as a function of cycle number for simulations with solvent contents of 31 (open triangles), 39 (closed triangles), 47 (open squares), 53 (closed squares), 59 (open circles) and 66% (closed circles). In each case the solvent mask used was based on the correct atomic model, except that the last approximately 10% of atoms in the structure were omitted in order to create an incorrect mask. All simulations were carried out as in Fig. 2 except for the starting phase sets. |