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Figure 5
Weakening of the hydrogen bond between Wat510 and Tyr77 OH at pH 8.0. Tyr77 in the native structure (2apr) is shown in black, in the complex with a reduced inhibitor (3apr) in dark grey and in the pH 8.0 form in light grey.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
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