Figure 1
Modular organization of the extracellular region of LDL-R. The `ligand-binding domain' and the `EGF precursor homology domain' are indicated. The cysteine-rich repeats R1–R7 are separated by short linkers of approximately four residues, with the exception of R4 and R5 which are separated by a 12-residue linker. The EGF-like repeats A, B and C flank the β-propeller domain. |