Figure 3
The active-site cleft of PTR1. The surface of subunit A is shown in grey, the surface of subunit B in green and Arg287′ from subunit D in blue. The cofactor and inhibitor are represented in stick mode and coloured according to atom type: N, blue; O, red; P, pink; C, yellow for NADPH and black for TAQ. Selected residues that line the active-site cleft are labelled. Figs. 3, 4 and 5 were prepared with PyMOL (DeLano, 2002). |