Figure 1
The phenazine-biosynthetic pathway in Pseudomonas. Chorismate is converted to phenazine-1-carboxylate by the enzymes encoded by the phzA–G operon. Biochemical and structural data have confirmed the roles of PhzE and PhzD in the conversion of chorismate to DHHA. Although the steps beyond the formation of DHHA are tentative and the exact structures of intermediates 1 and 2 have not been definitively proven, the scheme is consistent with currently available data (Parsons et al., 2004) |