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Figure 1
Comparison of the placement of the hepatitis C virus (HCV) core peptide 2–45 (red) in the lattice formed by the anti-HCV monoclonal antibody 19D9D6 (blue) and PpL (magenta) in the monoclinic P21 (a) and in the orthorhombic space group P21212 (b). In the situation above two peptides are ordered but the peptide sandwiched between two antigen-binding sites is disordered. In the P21212 lattice all peptides become ordered. Peptide aggregation is the possible cause of the problem in the P21 space group. Colour versions of the figures in this article are available in the online edition of the journal.

Journal logoBIOLOGICAL
ISSN: 1399-0047
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