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Figure 5
Hydrogen-bonding network of loops II and IV is conserved. (a) Despite the lack of a third disulfide in conkunitzin-S1, hydrogen bonding (indicated by yellow dashes) is strikingly similar to that observed in α-dendrotoxin (b) and BPTI (c), two proteins that retain the disulfide (orange). A buried water molecule (red sphere) helps to organize the hydrogen-bonding network in BPTI (c).

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
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