 | Acta Crystallographica Section D Acta Crystallographica Section D BIOLOGICAL CRYSTALLOGRAPHY |
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![[Figure 4]](gx5084fig4mag.jpg)
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Figure 4
X-ray scattering patterns and the model of Btk. (a) Experimental scattering from the Btk constructs (dots with error bars), computed scattering from ab initio models (red solid lines) and scattering from the models obtained by rigid-body refinement (blue dashed lines; for the kinase domain, computed scattering from its atomic structure). For PH-SH2 and full-length protein, scattering from models is displayed as green triangles. The plot displays the logarithm of the scattering intensity as a function of momentum transfer s = 4πsin(θ)/λ, where θ is the scattering angle and λ is the X-ray wavelength. The scattering patterns are appropriately displaced in the logarithmic scale for better visualization. (b) Superposition of a typical ab initio low-resolution model of the full-length Btk construct (semitransparent beads) with the Btk model obtained by rigid-body refinement of the positions of individual domains (colour-coded Cα chains). Typical conformations of interdomain linkers constructed by the program CREDO are displayed as blue Cα chains. |
![[Figure 4]](gx5084fig4.jpg)
| BIOLOGICAL CRYSTALLOGRAPHY |
ISSN: 1399-0047
