 | Acta Crystallographica Section D Acta Crystallographica Section D BIOLOGICAL CRYSTALLOGRAPHY |
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![[Figure 1]](ba5094fig1mag.jpg)
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Figure 1
(a) Schematic of an isothermal titration calorimeter. (b) Raw data output and (c) integrated data. (a) shows the sample cell and the reference cell in an isothermal jacket. The syringe is inserted in the sample cell and a series of injections are made. The injection of one component into the other results in an exothermic heat effect. After each injection, once the interaction is complete the power returns to an equilibrium value (b). The concentration regime between the two components is set up such that after a series of injections the binding sites available in the sample cell are gradually saturated. The profile of the binding isotherm (c) is fitted to obtain the thermodynamic parameters (see text). |
![[Figure 1]](ba5094fig1.jpg)
| BIOLOGICAL CRYSTALLOGRAPHY |
ISSN: 1399-0047
