Crystallization of protein–ligand complexes

Hassell, A.M.; An, G.; Bledsoe, R.K.; Bynum, J.M.; Carter, H.L.; Deng, S.-J.J.; Gampe, R.T.; Grisard, T.E.; Madauss, K.P.; Nolte, R.T.; Rocque, W.J.; Wang, L.; Weaver, K.L.; Williams, S.P.; Wisely, G.B.; Xu, R.; Shewchuk, L.M.

doi:10.1107/S0907444906047020

Acta Crystallographica Section D
Acta Crystallographica
Section D BIOLOGICAL CRYSTALLOGRAPHY

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Figure 7
Progesterone receptor LBD. Cocrystals of the ligand of interest were obtained when the protein was initially expressed with a lower affinity ligand. The ligand of interest was then added in molar excess and included throughout protein purification.

BIOLOGICAL
CRYSTALLOGRAPHY

ISSN: 1399-0047

Volume 63| Part 1| December 2007| Pages 72-79

doi:10.1107/S0907444906047020

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