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Figure 4
(a) The bottom panel shows a schematic representation of a two-dimensional 1H–15N correlation spectrum. Peaks in this spectrum can be assigned to amide NH pairs in the protein backbone. (b) On addition of a ligand, NH pairs close to the binding molecule will be selectively perturbed, allowing the binding site to be localized.

Journal logoBIOLOGICAL
CRYSTALLOGRAPHY
ISSN: 1399-0047
Volume 63| Part 1| December 2007| Pages 62-71
doi:10.1107/S0907444906051869
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