 | Acta Crystallographica Section D Acta Crystallographica Section D BIOLOGICAL CRYSTALLOGRAPHY |
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![[Figure 4]](be5087fig4mag.jpg)
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Figure 4
Phasing based on isomorphous signal. (a) SIR case, with the measured native protein amplitude shown in brown, the derivative amplitude in blue and the calculated contribution of the substructure in purple. There are two possible solutions and the initial average protein phase φoSIR corresponds to the phase of the heavy-atom substructure. (b) If the handedness of the substructure is inverted, the phase of the substructure as well as the average protein phase φcSIR are reversed, φcSIR = −φoSIR. (c) If there is more than one derivative, it is possible to select the correct phase where the individual indications from all derivatives coincide. |
![[Figure 4]](be5087fig4.jpg)
| BIOLOGICAL CRYSTALLOGRAPHY |
ISSN: 1399-0047
