The structure of the BIR3 domain of cIAP1 in complex with the N-terminal peptides of SMAC and caspase-9

Kulathila, R.; Vash, B.; Sage, D.; Cornell-Kennon, S.; Wright, K.; Koehn, J.; Stams, T.; Clark, K.; Price, A.

doi:10.1107/S0907444908039243

Acta Crystallographica Section D
Acta Crystallographica
Section D BIOLOGICAL CRYSTALLOGRAPHY

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Figure 5
Overlay of cIAP1-BIR3 and XIAP-BIR3. The C^α-atom traces of the proteins are shown. cIAP1-BIR3 is shown in magenta and XIAP-BIR3 in gray. The conformation of cIAP-BIR3 from the caspase-9 peptide complex (this work) is superimposed on the XIAP-BIR3 structure as seen in the protein–protein complex of XIAP-BIR3 and caspase-9 (Shiozaki et al., 2003

). The coordinated zinc ion is shown in magenta.

BIOLOGICAL
CRYSTALLOGRAPHY

ISSN: 1399-0047

Volume 65| Part 1| December 2009| Pages 58-66

doi:10.1107/S0907444908039243

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