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Figure 1
A simple model of hypothesis-driven research in the experimental natural sciences. Prior knowledge leads to a question that can hopefully be answered by carrying out one or more experiments. The observations and the prior knowledge are combined to yield a hypothesis or model, which can be used to make falsifiable predictions. In the case of crystallography, the model consists of the parameterization and the optimal values derived for all parameters.

Journal logoBIOLOGICAL
CRYSTALLOGRAPHY
ISSN: 1399-0047
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