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Figure 1
Structural overview of the complete 12-subunit RNA polymerase II elongation complex (Kettenberger et al., 2004BB23). Two views are shown of a ribbon model of the protein subunits and nucleic acids, a side view (a) and a top view (b), related by a 90° rotation around a horizontal axis. The polymerase subunits Rpb1–Rpb12 are coloured according to the key shown below. Template DNA, nontemplate DNA and product RNA are shown in blue, cyan and red, respectively. P atoms are indicated as spheres and extrapolated B-form downstream DNA is coloured light pink. Eight zinc ions and the active-site magnesium ion are depicted as cyan spheres and a magenta sphere, respectively. This colour code is used throughout. Secondary-structure assignments for Pol II are according to Cramer et al. (2001BB14) and Armache et al. (2005BB2). This figure was adapted from Kettenberger et al. (2004BB23) with modifications.

Journal logoBIOLOGICAL
CRYSTALLOGRAPHY
ISSN: 1399-0047
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