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Figure 2
Structural details of the Pol II elongation complex. (a) Overview of the EC structure (Kettenberger et al., 2004BB23). The view is as in Fig. 1[link](a). (b) Superposition of NTP-binding sites [red, insertion site (Westover et al., 2004aBB49; Wang et al., 2006BB47); violet, entry site (Westover et al., 2004aBB49); pink, inactive pre-insertion-like state in which the triphosphate is too far from the catalytic metal ion A to allow incorporation (Kettenberger et al., 2004BB23)]. (c) Functional Pol II surface elements in the EC highlighted in yellow. This figure was adapted from Cramer et al. (2008BB12).

Journal logoBIOLOGICAL
CRYSTALLOGRAPHY
ISSN: 1399-0047
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