Figure 1
Variation in mean validation criteria over time, comparing the structures deposited from 1972 to 1985 with matched structures deposited over subsequent periods. Error bars in this and subsequent figures indicate the estimated standard uncertainty of the mean, computed as the sample standard deviation divided by the square root of the number of observations. (a) Overall average G value computed by PROCHECK (Laskowski et al., 1993). (b) Percentage Ramachandran outliers determined using the criteria established by Kleywegt & Jones (1996). |