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Figure 3
Comparison between human KHK-A and E. coli ribokinase. Ribbon diagrams are shown of KHK-A, of KHK-C and of E. coli ribokinase in the presence (PDB code 1rkd) and absence (PDB code 1rka) of ribose and ADP. The green subunit is shown in the same orientation in all structures. The alternative splicing of the KHK gene results in a different sequence for a single region of the chain between the two isoforms (residues 72–115), which is shown in red. These figures were generated using PyMOL (DeLano, 2002 ![]() |