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![[Figure 5]](be5117fig5mag.jpg)
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Figure 5
Substrate and cofactor interactions in the active site. (a) Schematic diagram of the KHK-A active site; thin lines show the hydrogen-bond interactions (≤3.2 Å) between the substrate and cofactor and the surrounding protein residues and water molecules. This figure was generated using ISIS/Draw 2.2.1 (MDL Information Systems). (b) Ribbon diagram showing the active site, with the residues interacting with the fructose and AMP-PNP shown in stick representation. |
![[Figure 5]](be5117fig5.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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