Figure 2
Alignment of amino-acid sequences from nsp4ct proteins, coupled with secondary-structure information from the FCoV nsp4ct three-dimensional structure. The alignment is based on amino-acid data for feline infectious peritonitis virus (FCoV, NC_007025.1), human coronavirus NL63 (HCoV, ABE97129), murine hepatitis virus (MHV, NP_001012459.1), severe acute respiratory syndrome coronavirus (SARS_CoV, NP_904322.1) and infectious bronchitis virus strain Beaudette (IBV, NP_740625). The alignment was produced with ClustalW2 (Larkin et al., 2007) and edited with JalView. Residues are coloured according to conservation from fully conserved (dark blue) to nonconserved (colourless). |