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Figure 2
Modelling the data statistics for a cubic insulin crystal. (a) The signal-to-noise ratio, , at a resolution h−1 = 1.5 Å for five sequential frames of Δφ = 1° and a |Φ| = 5° wedge of data versus the exposure time per frame. The calculations were carried out with (black line) and without (red line) accounting for radiation damage. (b) Signal-to-noise ratio and graphical solution of a set of equations (§ 2.2.2) at a resolution of 1.5 Å for three progressive subwedges. The signal-to-noise target was C = 2, Δφ was fixed at 1° and |Φ| = 5°. No solution was possible for the third subwedge. (c) The same as (b) for four consecutive wedges and resolution 1.55 Å. |


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