Figure 29
Cross-crystal averaging of hemagglutinin–neuraminidase (HN). Left, the unit cell showing the 6.0 Å resolution MIR map derived from eight heavy-atom derivatives contoured at 2.0σ, revealing two blobs corresponding to the two molecules in the asymmetric unit. Right, a section of the 2.0 Å resolution map after phase extension and cross-crystal averaging over four non-isomorphous data sets. |