Structure of Staphylococcus aureus adenylo­succinate lyase (PurB) and assessment of its potential as a target for structure-based inhibitor discovery

Fyfe, P.K.; Dawson, A.; Hutchison, M.-T.; Cameron, S.; Hunter, W.N.

doi:10.1107/S0907444910020081

Acta Crystallographica Section D
Acta Crystallographica
Section D BIOLOGICAL CRYSTALLOGRAPHY

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Figure 1
PurB catalyzes two reactions: the conversion of SAICAR to AICAR (a) and the conversion of adenylosuccinate to AMP (b). In each case fumarate is also produced.

BIOLOGICAL
CRYSTALLOGRAPHY

ISSN: 1399-0047

Volume 66| Part 8| July 2010| Pages 881-888

doi:10.1107/S0907444910020081

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