Figure 4
(a) Homohexamer predicted by PISA for PDB entry 1qex
. (b) 1qex
homotrimer identified as the biological unit in an experimental study by Rossmann et al. (2004); the hexamer is predicted to dissociate into two trimers. (c) Alternative homotrimer 1s2e
obtained by different main-chain tracing in the same electron-density maps as 1qex
; 1s2e
trimers are correctly identified by PISA as not forming stable hexamers. See discussion in the text. The images were produced using the CCP4mg graphical viewer (Potterton et al., 2004). |