Figure 1
Thermofluor assay and Tm histogram. (a) According to the results of the Thermofluor experiment samples can be classified into three groups: those producing a sharp sigmoidal denaturation curve (left panel), those with no clear temperature transition (centre) and those with complex denaturation curves. The crystallization success rates for each of these groups are indicated. (b) Histogram of Tm for the 437 samples producing single sigmoidal curves. The numbers over the bars indicate the number of samples in the class. |