Figure 5
General displacement between structures at a series of pressures. The vectors between the Cα positions of the atmospheric and the high-pressure structures are represented as arrows (yellow, 340 MPa–0.1 MPa; orange, 410 MPa–0.1 MPa; red, 580 MPa–0.1 MPa). For an easier visualization, the lengths of the vectors are magnified eight times. (a) and (b) are enlarged views of Figs. 3(a) and 3(b), respectively. Simultaneous opening of the groove and closure of the active-site entrance can be observed. The double arrow in (b) emphasizes the vectors that represent the large motion described by the Lys81–Glu86 loop. |