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Figure 5
General displacement between structures at a series of pressures. The vectors between the Cα positions of the atmospheric and the high-pressure structures are represented as arrows (yellow, 340 MPa–0.1 MPa; orange, 410 MPa–0.1 MPa; red, 580 MPa–0.1 MPa). For an easier visualization, the lengths of the vectors are magnified eight times. (a) and (b) are enlarged views of Figs. 3 (a) and 3 (b), respectively. Simultaneous opening of the groove and closure of the active-site entrance can be observed. The double arrow in (b) emphasizes the vectors that represent the large motion described by the Lys81–Glu86 loop. |


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