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![[Figure 2]](yt5043fig2mag.jpg)
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Figure 2
Characterization of the inhibition of Eg5 by ispinesib. Inhibition of the (a) basal and (b) MT-stimulated ATPase activity of Eg5. (c) Raw (top) and integrated (bottom) ITC data demonstrating saturable exothermic evolution of heat upon sequential additions of ispinesib to Eg5. 1 cal = 4.184 J. |
![[Figure 2]](yt5043fig2.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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