Active site of 6-P-β-glucosidase (stereoview). (a) LpPgb1 in complex with a phosphate anion and an aglycon β-glucose moiety. Hydrogen bonds are shown as broken lines. (b) E375Q SmBgl in complex with 6′-P-salicin. For comparison, the aglycon glucose molecule from the LpPgb1 structure is shown in green. (c) SmBgl in complex with 6-P-β-glucose. All ligands are shown as 2Fo − Fc electron-density maps contoured at the 1σ level.