 | Acta Crystallographica Section D Acta Crystallographica Section D BIOLOGICAL CRYSTALLOGRAPHY |
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![[Figure 2]](ic5087fig2mag.jpg)
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Figure 2
The scales of structural biology and their relationship to the currently available archives (EMDB and PDB): from the atomic details and interactions in a binding site to the cellular context of molecular machines, illustrated using the ribosome as an example. From left to right: soft X-ray tomogram of a fission yeast cell (adapted from Larabell & Nugent, 2010  with permission of Elsevier), electron tomogram of ribosomes in the cytosol (EMDB entry EMD-5227; Brandt et al., 2010), cryo-EM reconstruction of the 80S ribosome from yeast (EMDB entry EMD-2008; Becker et al., 2012), crystal structure of the 50S ribosomal subunit (PDB entry 3uzk
; Demeshkina et al., 2012) and crystal structure revealing how tmRNA and the small protein SmpB enable the kirromycin-stalled 70S ribosome to proceed with translation (PDB entries 4abr
and 4abs
; Neubauer et al., 2012). |
![[Figure 2]](ic5087fig2.jpg)
| BIOLOGICAL CRYSTALLOGRAPHY |
ISSN: 1399-0047
