 | Acta Crystallographica Section D Acta Crystallographica Section D BIOLOGICAL CRYSTALLOGRAPHY |
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![[Figure 4]](be5232fig4mag.jpg)
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Figure 4
Cobalamin-binding site in CobDH. The cobalamin and the conserved residues Asp100, His102 and Ser147 are shown as sticks (C atoms coloured grey) and are labelled using the single-letter amino-acid codes for clarity. Asp100 hydrogen-bonds to His102 (2.7 Å distance), which in turn is coordinated to the Co atom of the cofactor from the lower axial site (2.5 Å distance). The side chain of Ser147 forms a hydrogen bond to an N atom of the dimethylbenzimidazole (DMB) of the cobalamin (2.7 Å distance). The interactions described are indicated with green dotted lines. The blue mesh corresponds to a 2Fo − Fc map with the cobalamin and the key residues omitted from map calculations. The map was contoured at 2.0σ. |
![[Figure 4]](be5232fig4.jpg)
| BIOLOGICAL CRYSTALLOGRAPHY |
ISSN: 1399-0047
