 | Acta Crystallographica Section D Acta Crystallographica Section D BIOLOGICAL CRYSTALLOGRAPHY |
journal menu
![[Figure 3]](ba5202fig3mag.jpg)
|
|
Figure 3
Solution of the structure of the ternary complex of Escherichia coli dehydrodipicolinate reductase: following the positioning of the central core, the structure was completed using a single N-terminal domain as a search model and the difference Fourier maps generated from the partial solution as the search space. NCS was then used to place two of the remaining three N-terminal domains. The fourth was built into available density following several rounds of refinement of the partial model. The final model revealed that three of the four subunits are in a closed conformation in the ternary complex, with both cofactor and substrate bound to the enzyme, while the fourth subunit is unliganded and in an open conformation. |
![[Figure 3]](ba5202fig3.jpg)
| BIOLOGICAL CRYSTALLOGRAPHY |
ISSN: 1399-0047
