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Figure 3
F1 occupies the nucleoside-binding site of dCK. The left panel shows an overlay of dCK–F1–UDP (green ribbon) with dCK–5Br-dC–UDP (gray ribbon; PDB entry 3qen ; r.m.s.d. of 0.36 Å over 196 Cα atoms). The enlargement in the right panel demonstrates the nearly perfect overlay of the pyrimidine rings of F1 and 5Br-dC and a conserved hydrogen-bond network (represented as dashed lines).

Journal logoBIOLOGICAL
CRYSTALLOGRAPHY
ISSN: 1399-0047
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