Figure 3
Remodeling of Lys84, predicted to be carboxylated, to Kcx84 in carbapenemase OXA-24 (PDB entry 2jc7
). (a) shows Lys84 highlighted in stick representation as reported in the structural coordinates (Santillana et al., 2007). The 2Fo − Fc electron-density map around Lys84 is shown as a gray mesh and is contoured at 1σ. The Fo − Fc map is shown in green and is contoured at 3σ. (b) shows the 2Fo − Fc map around Lys84 after refinement with REFMAC (Murshudov et al., 2011) and with the Lys84 modified to include the PTM. This figure was created with PyMOL (Schrödinger; https://www.pymol.org
). |